1 factor, in 2 convenient vial sizes1
Preparing, reconstituting, and administering VONVENDI® [von Willebrand factor (Recombinant)]
VONVENDI is available as a non-pyrogenic lyophilized powder for reconstitution in single-use vials containing nominally 650 or 1300 international units VWF:RCo per vial.1
- Each package includes VONVENDI, Sterile Water for Injection (sWFI), one MIX2VIAL® reconstitution device, one full prescribing physician insert, one patient insert, and one instructions for use1
- The actual product strength will be printed on the vial label and on the box1
Preparation and Reconstitution1
- Allow VONVENDI and sterile Water for Injection (diluent) to reach room temperature if it has been refrigerated
- If the patient requires more than one vial of VONVENDI per injection, reconstitute each vial separately according to the following instructions
Reconstitution and Administration guidelines1
- Administer VONVENDI immediately after reconstitution. If not, store at room temperature not to exceed 25°C (77°F) for up to 3 hours. Discard after 3 hours
- If a patient is to receive more than one vial of VONVENDI, the contents of up to two vials may be pooled into a single syringe. Pooling of more than two vials into a syringe may result in formation of filaments, which requires discarding of the solution in the syringe. Leave syringe attached to the vial or cover syringe tip with a suitable sterile cap until ready to infuse to reduce risk of contamination
- Use plastic syringes with this product because proteins in the product tend to stick to the surface of glass syringes
- Do not mix VONVENDI with other medicinal products
Reconstitution and Administration1
Please see the VONVENDI full Prescribing Information for the eight complete steps required to reconstitute VONVENDI and the nine complete steps required to administer VONVENDI.1
VONVENDI may be stored at room temperature (≤30°C/86°F) for the life of the product1
Store at room temperature not to exceed 30°C (86°F) or at refrigerated temperature 2°C to 8°C (36°F to 46°F)
- Do not freeze
- Store in the original box and protect from extreme exposure to light
- Do not use beyond the expiration date printed on the VONVENDI vial label or carton
- Use reconstituted product immediately or within 3 hours after reconstitution
- Discard any unused reconstituted product after 3 hours
Register For Updates
Stay up to date with the latest news and information
Patient Support
Patients can receive additional treatment support with the help of our dedicated team
Contact a Takeda Rep
Get in touch with a Takeda representative in your area